They are not wrinkle free, which would require a very high polyester content. Our natural fiber cotton lab coats are wrinkle resistant, thanks to a patented finishing process that we use. The clearest analogy that we can give, is if you prefer to iron your khakis or your jeans, then you likely will want to press your Medelita lab coat. Others who don’t necessarily want a pristine, crisp finish, are fine with pulling their lab coat out of the dryer early in the dryer cycle, then hanging to dry, with great results.